The Binding of Isaac: Rebirth on Radeon RX 550

Well above recommendedEstimate · low confidence, ±30%

Yes. The Radeon RX 550 is well above The Binding of Isaac: Rebirth's recommended spec. We estimate ~168 fps at 1080p high (range 118–218, low confidence, ±30%), GPU-limited. At 1440p high expect ~118 fps, so every preset holds 60 fps. Model estimate, not measured; data updated 2026-09-24.

Estimated FPS by preset

Preset1080p1440p4K
low286200120
medium21815392
high16811871
ultra1349456
Estimate · low confidence, ±30%

Estimated FPS from our model (v0), based on the game's published requirements and relative GPU/CPU performance. Not measured. Real results vary with drivers, patches, and scenes. Values above 300 fps show as 300+. Data updated 2026-09-24.

Best settings

  • 60 fps at 1080p: ultra preset
  • 60 fps at 1440p: ultra preset
  • 144 fps at 1080p: high preset

AMD card: use FSR in quality mode before dropping the preset (XeSS also works). DLSS is not available on Radeon.

What limits performance

  • Estimates above: GPU-limited, assuming a processor fast enough not to hold the Radeon RX 550 back.
  • Processor needed for ~168 fps: Core i3-9100F or faster (slowest current desktop CPU our model expects to keep up).
  • With the recommended CPU: CPU-limited at 1080p high: about 90 fps instead of 168.

Video memory

  • Radeon RX 550: 4 GB
  • The publisher lists no video memory requirement.

The Binding of Isaac: Rebirth on popular graphics cards (high preset)

Graphics card1080p1440pvs Radeon RX 550
Radeon RX 550168118—
GeForce GTX 1650300+300++186%
GeForce GTX 1060 6GB300+300++300%
GeForce RTX 2060 6GB300+300++500%
Radeon RX 6600300+300++557%
GeForce RTX 3060 12GB300+300++614%
GeForce RTX 4060 Laptop GPU300+300++643%
Radeon RX 7600300+300++729%
GeForce RTX 4060300+300++743%
GeForce RTX 3070300+300++886%
GeForce RTX 4070300+300++1143%
Radeon RX 7800 XT300+300++1286%
GeForce RTX 5070300+300++1329%
Radeon RX 9070 XT300+300++1757%
GeForce RTX 4080300+300++1829%
GeForce RTX 5090300+300++2971%

The Binding of Isaac: Rebirth on other hardware

More about the Radeon RX 550

Specs and every game it runs →The Binding of Isaac: Rebirth requirements and FPS on popular hardware →Best GPUs for The Binding of Isaac: Rebirth →